What is “Translational Research”?
To improve human health, scientific discoveries must be translated into practical applications. These discoveries typically begin at “the bench” with basic research, in which scientists study disease at the molecular and cellular levels, then progress to the clinical level, or the patient’s “bedside.”
This “bench-to-bedside” approach in translational research is actually a two-way street. Basic scientists provide clinical researchers with new patient care tools to assess through clinical trials, and clinical researchers make novel observations about the nature and progression of disease that often stimulate basic scientists’ investigations.
The combined efforts of scientists, researchers, and physicians make translational research a true interdisciplinary approach to improving lives through innovation that leads to discoveries and ultimately cures.
What is the TRI?
The Translational Research Institute for Metabolism and Diabetes (TRI) is the product of an innovative affiliation between Florida Hospital and Sanford Burnham Medical Research Institute. By linking the largest healthcare provider in Central Florida with a nationally renowned basic science leader, the TRI bridges the gap between the research bench and the patient’s bedside.
At a state of the art facility located on the Florida Hospital Campus, a talented team of brilliant researchers and experienced, caring medical professionals is bringing medical discoveries from the laboratory to the community for further testing, through clinical trials, in an effort to tackle some of today’s biggest health problems – obesity, diabetes, and cardiovascular disease.
Why Metabolism & Diabetes?
We are witnessing an obesity and diabetes pandemic. In the United States alone, more than 60 percent of adults are overweight or obese. Type 2 diabetes, which is driven by excessive body weight, has increased nearly 30 percent in the last decade. Children are increasingly obese, and some are beginning to develop insulin resistant forms of diabetes that were rare in children just 10 years ago. Diabetes is often accompanied by an aggressive form of cardiovascular disease and greatly increases the risk of atherosclerosis and heart failure.
The specific roles of metabolism and other mechanisms in obesity, diabetes and cardiovascular disease remain unclear. Understanding these mechanisms require an interdisciplinary approach; hence, the development of the Translational Research Institute for Metabolism and Diabetes.