Research Study

Past Study: ISTARmicro


Study Status: CLOSED

Study Name: ISTARmicro

Study Focus: Artificial sweetners



Study Contact: To learn more, please call 1-877-854-8475 or fill out the Contact us form.

Study Purpose: The purpose of this study is to collect data to examine whether short-term consumption of non-caloric artificial sweeteners (NCASs), such as saccharin, can lead to changes in your blood sugar levels and in the composition of the bacteria in your large intestine. The community of intestinal bacteria is called the gut microbiota. Several studies have shown an association between gut microbiota and diseases like obesity and diabetes. Your intestine also carries some specialized receptors for sensing sweet nutrients, such as sugars and NCASs. These sensors are called sweet taste receptors (STRs) which are also found on your tongue, allowing you to taste the "sweetness" of the food you consume. This study will improve our understanding on how NCASs may be able to modify your gut microbiota and blood sugar and whether blocking the function of STRs can prevent these changes.

To be enrolled in this study, you must meet certain requirements. You may be eligible to participate if you meet the associated criteria:

  • BMI ≤25 kg/m2
  • Stable weight
  • Age: 18-45 years old
  • Good general health
  • Do not use non-caloric artificial sweeteners

Study Procedures:

  •  Blood draw
  • Urine and stool collection
  • Physical exam
  • Consumption of non-caloric artificial sweeteners

Study Commitment: up to 6 weeks

  • Total of 4 visits (1 screening visit and 3 outpatient visits)

Compensation offered? Yes This study is being conducted under the direction of Dr. George Kyriazis, at 301East Princeton Street, Orlando, Florida 32804.